Topical CBD for Pain - A Primer for Clinicians

Dr. Corroon collaborated with Dr. Jake Felice on this peer-reviewed article about topical CBD products.

Abstract

Given the high tolerability, positive safety profile, and low risk of drug interactions of topical products derived from Cannabis spp, the administration of them for chronic pain may represent an underutilized form of therapy. This article reviews the limited animal and human studies investigating cutaneous applications of cannabinoids and cannabis-derived products, with a focus on cannabidiol (CBD) and its potential mechanisms of action. Animal models show topical penetration of cannabinoids into underlying tissues, as well as dose-dependent anti-inflammatory and pain-relieving effects. While randomized, controlled trials are needed to substantiate anecdotal claims of efficacy in humans, evidence exists to warrant clinical exploration of these products by healthcare professionals.

Read the article here.